hotel banner

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Welcome to South San Francisco

Check-in: 4:00 PM|Checkout: 11:00 AM

Enjoy the suite life at our Sonesta ES Suites San Francisco Airport Oyster Point Waterfront hotel. Each suite features a fully equipped kitchen, roomy work area, free WiFi, and bigger, cozier beds. In the morning, you will enjoy free breakfast with fresh coffee and a variety of offerings. Whether you’re here for business, leisure, or a long-term stay, our all-suite hotel has all you need to feel right at home and much more. 

Our hotel is conveniently located less than a mile from top corporations including Kaiser, Amgen, and Thermo Fisher. Just a short drive away, you will find Genentech and UCSF Medical Center. We make sure your stay is surprisingly different by combining affordability with conveniences like everyday surprises, complimentary treats, and other unexpected delights. It’s no wonder we’re a favorite among business travelers and families for hotels in San Francisco, CA.

Extend Your Expectations with Sonesta ES Suites.

Read More +

Get Together in San Francisco

From sports teams to business conferences—easily book your group travel with us.


Select Your Room

Travel Agents: Visit our partner portal to book with your agent ID.
Explore Sonesta
Explore All Offers
Daylight Saving Season

Daylight Saving Season

Book your spring getaway by April 30 and save as much as 30%, plus earn bonus Travel Pass Points.

AAA/CAA Member Discount

AAA/CAA Member Discount

Receive 5% off of the Best Available Rate with your AAA or CAA membership!

Planning Comes with Perks

Planning Comes with Perks

Save up to 15% when you book seven or more days in advance.

Explore the Area

What's Nearby

About The Hotel
Hotel Details

Our Hotel in San Francisco, CA

At the Sonesta ES Suites San Francisco Airport Oyster Point Waterfront, we’re community-inspired. Here, you're part of a community where smiles are genuine and everyday surprises brighten your stay, whether you're with us for a night or a month. We're easy to find and centrally located near top attractions such as the Kaiser, Amgen, and Thermo.

Our oversized suites have fully-equipped kitchens for the ultimate convenience at mealtime. And you’ll enjoy attentive service, everyday surprises that brighten your stay and much more. Plus, you can take advantage of amenities like free breakfast and free WiFi. We aim to make convenience and ease synonymous with Sonesta ES Suites, whether you’re here for business or pleasure.